Data Management






Data Management
Implement Data Management Solutions to Satisfy Increased Computing Power
29/11/2023 - 30 November 2023 ALL TIMES EST
With the increased demand in computing power from life science researchers and scientists tackling big data issues, data storage infrastructure must be able to scale to handle billions of data points and files efficiently. The problem is administration of data to ensure information can be integrated, accessed, shared, linked, analyzed, and maintained to effect change across the organization. How do you make sense of data and its content to create value? The Data Management track will explore these questions and other themes related to FAIR data, data reuse/governance/literacy, data federation, and standards/data curation/harmonization.

Wednesday, 29 November

Registration and Morning Coffee

Plenary Keynote

PLENARY KEYNOTE PROGRAM

Chairperson's Remarks

Allison Proffitt, Editorial Director, Bio-IT World and Clinical Research News , Editorial Dir , Bio-IT World

Welcome Remarks

Photo of Laila Cunningham, Lancaster Gate Councillor, City of Westminster , Lancaster Gate Councillor , City of Westminster
Laila Cunningham, Lancaster Gate Councillor, City of Westminster , Lancaster Gate Councillor , City of Westminster

PLENARY KEYNOTE CO-PRESENTATION:
MOSAIC: A Global Initiative to Deploy Spatial Omics and AI against Cancer

Photo of Barbara Domayne-Hayman, DPhil, Entrepreneur-in-Residence, Francis Crick Institute , Entrepreneur-in-residence , Francis Crick Institute
Barbara Domayne-Hayman, DPhil, Entrepreneur-in-Residence, Francis Crick Institute , Entrepreneur-in-residence , Francis Crick Institute
Photo of Markus Eckstein, MD, Senior Consultant in Surgical Pathology, Institute of Pathology of FAU Medical School and University Hospital Erlangen/UKER , Senior Consultant in Surgical Pathology , Institute of Pathology of , FAU Medical School and University Hospital Erlangen/UKER
Markus Eckstein, MD, Senior Consultant in Surgical Pathology, Institute of Pathology of FAU Medical School and University Hospital Erlangen/UKER , Senior Consultant in Surgical Pathology , Institute of Pathology of , FAU Medical School and University Hospital Erlangen/UKER
Photo of Raphael Gottardo, PhD, Professor and Director, Biomedical Data Science Center, Lausanne University Hospital and University of Lausanne , Full Professor and Director , Biomedical Data Science Center , Lausanne University Hospital
Raphael Gottardo, PhD, Professor and Director, Biomedical Data Science Center, Lausanne University Hospital and University of Lausanne , Full Professor and Director , Biomedical Data Science Center , Lausanne University Hospital
Photo of Joseph Lehár, PhD, Senior Vice President Business Strategy, OWKIN , Senior Vice President R&D Strategy , OWKIN
Joseph Lehár, PhD, Senior Vice President Business Strategy, OWKIN , Senior Vice President R&D Strategy , OWKIN

In June, Owkin and world-leading Cancer research institutions and technology companies from the US, France, Germany, and Switzerland unveiled MOSAIC, a $50 million initiative to use spatial omics technologies at unprecedented scale. The aim is to analyze the tumor microenvironment of more than a thousand patients in each of seven difficult-to-treat cancers and to develop and apply AI/ML tools to develop a spatial omics atlas that will help to advance novel therapies. In this session, we will present the scientific vision, the aims and role of participating institutions, and an update on progress in the project's first six busy months.

Grand Opening Coffee Break in the Exhibit Hall with Poster Viewing

ROLE OF DATA IN GENERATING BIOLOGICAL INSIGHTS

Organizer's Remarks

Eileen Murphy, Conference Producer, Cambridge Healthtech Institute , Conference Producer , Cambridge Healthtech Institute

Chairperson's Remarks

Ben Busby, PhD, Global Alliances Manager, Omics, NVIDIA , Global Alliances Manager, Omics , NVIDIA

Panel Moderator:

PANEL DISCUSSION:
Developing and Using Large- and Small-Scale TREs for Generating Biological Insights

Photo of Ben Busby, PhD, Global Alliances Manager, Omics, NVIDIA , Global Alliances Manager, Omics , NVIDIA
Ben Busby, PhD, Global Alliances Manager, Omics, NVIDIA , Global Alliances Manager, Omics , NVIDIA

Panelists:

Photo of Lora Boteva, PhD, Senior Data Analyst, UK Biobank , Senior Data Analyst , UK Biobank
Lora Boteva, PhD, Senior Data Analyst, UK Biobank , Senior Data Analyst , UK Biobank
Photo of Asha Collins, PhD, Senior Vice President & General Manager, Biobanks, DNAnexus , SVP and General Manager, Biobanks , DNAnexus
Asha Collins, PhD, Senior Vice President & General Manager, Biobanks, DNAnexus , SVP and General Manager, Biobanks , DNAnexus
Photo of Robin Hofmeister, Postdoctoral Researcher, Statistical Genetics Group, University of Lausanne , Postdoctoral Researcher - Statistical Genetics Group , University of Lausanne
Robin Hofmeister, Postdoctoral Researcher, Statistical Genetics Group, University of Lausanne , Postdoctoral Researcher - Statistical Genetics Group , University of Lausanne

Networking Lunch in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)

DATA MINING, MODELING, MAPPING, AND COMPLIANCE CHALLENGES TO ADVANCE BIOMEDICAL RESEARCH AND DISCOVERY EFFORTS

Chairperson's Remarks

Christopher Southan, PhD, Honorary Professor, Deanery of Biomedical Sciences, University of Edinburgh , Honorary Professor, Deanery of Biomedical Sciences , University of Edinburgh

CO-PRESENTATION:
ICD10 Mapping and Biomarker Profiling Using UK Biobank Data to Improve Phenome-Wide Association Studies

Photo of Manik Garg, PhD, Senior Data Scientist, AstraZeneca , Senior Data Scientist , AstraZeneca
Manik Garg, PhD, Senior Data Scientist, AstraZeneca , Senior Data Scientist , AstraZeneca
Photo of Jennifer Harrow, PhD, Director of Phenomic Data Operations, Centre for Genomic Research, AstraZeneca , Director of Phenomic Data Operations , Centre for Genomic Research , AstraZeneca
Jennifer Harrow, PhD, Director of Phenomic Data Operations, Centre for Genomic Research, AstraZeneca , Director of Phenomic Data Operations , Centre for Genomic Research , AstraZeneca

Genomic programs that want to increase numbers and extend ancestry in their biobanks, need to address the differences in phenomic data classification. Projects wanting to harmonize their clinical cohorts across projects need to understand the context of their biobanks and the intent of their project. I will discuss the UK Biobank (UKB) study containing detailed phenotypic data linked to medical records for approximately 500,000 participants and remapping ICD-9 to ICD10 WHO versions. You will learn about finding the ontology mapping in real-world evidence, transition from manual to automation methods, and challenges along with biomarker profiling to identify “missing cases”. 

Unique Open Curated SAR Data from Patents in PubChem

Photo of Christopher Southan, PhD, Honorary Professor, Deanery of Biomedical Sciences, University of Edinburgh , Honorary Professor, Deanery of Biomedical Sciences , University of Edinburgh
Christopher Southan, PhD, Honorary Professor, Deanery of Biomedical Sciences, University of Edinburgh , Honorary Professor, Deanery of Biomedical Sciences , University of Edinburgh

The large-scale automated extraction of chemical structures from patent documents by IBM, Google, WIPO and SureChEMBL have contributed over 40 million CIDs to PubChem but present major data quality filtration challenges. To facilitate community exploitation BindingDB has manually curated structure activity (SAR) data for ~0.4 million compounds from ~ 6000 patents. The data has recently been included in  ~ 12K new BioAssays in PubChem. An example from Abvie US9796708 "Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors", as BioAssay AID: 1797504 includes 1,352 IC50 values. The data mining opportunities these present, including AI modeling, will be outlined.

Decoding EU Privacy Legislation: Data Compliance Challenges and Solutions for Life Sciences

Photo of Ben Seretny, Head of DPOs, The DPO Centre Ltd. , Head of DPOs , The DPO Centre
Ben Seretny, Head of DPOs, The DPO Centre Ltd. , Head of DPOs , The DPO Centre

Ben Seretny, Head of DPOs, will provide valuable insights into EU/UK privacy laws and how life sciences organisations can increase patient and trial participant trust and engagement by implementing robust compliance processes. 

  • Overview of EU/UK privacy legislation and why it is applicable to organisations worldwide
  • The many implications of processing personal data of EU/UK residents
  • EU clinical trial regulations, including the CTIS and other jurisdictional challenges
  • EU/UK data protection officers and representatives: when and why are they required??

Session Break and Transition to Plenary Keynote

Plenary Keynote

PLENARY KEYNOTE FIRESIDE CHAT

Chairperson’s Remarks

Allison Proffitt, Editorial Director, Bio-IT World and Clinical Research News , Editorial Dir , Bio-IT World

PLENARY KEYNOTE FIRESIDE CHAT:
Data Citizenship and Changing Data Culture

Photo of Stan Gloss, Co-Founder and Fellow, BioTeam, Inc.; Podcast Host, Trends in the Trenches , Co-Founder & Fellow , BioTeam, Inc.
Stan Gloss, Co-Founder and Fellow, BioTeam, Inc.; Podcast Host, Trends in the Trenches , Co-Founder & Fellow , BioTeam, Inc.
Photo of Bryn Roberts, PhD, Global Head of Data & Analytics, Roche Information Solutions , Global Head of Data & Analytics , Roche Information Solutions
Bryn Roberts, PhD, Global Head of Data & Analytics, Roche Information Solutions , Global Head of Data & Analytics , Roche Information Solutions

With thirty years of experience in informatics and data and big pharma positions at Roche and AstraZeneca, Bryn Roberts has a unique perspective on the data-growing pains now facing life sciences. Within life sciences organizations, there are both responsibilities and privileges associated with data production and use, he says. Data producers should share data within certain parameters, and data consumers should use and credit data fairly, he believes. In this fireside chat, Stan will interview Bryn who will share his insights into the state of data right now in life sciences, why data citizenship is the paradigm shift we all need to embrace, how to truly create a FAIR data culture, and how artificial intelligence and machine learning will most impactfully change our data landscape.

Welcome Reception in the Exhibit Hall with Poster Viewing

Close of Day

Thursday, 30 November

Registration and Morning Coffee

Plenary Keynote

PLENARY KEYNOTE PROGRAM

Chairperson’s Remarks

Cindy Crowninshield, Executive Event Director, Cambridge Healthtech Institute , Executive Event Director , Cambridge Healthtech Institute

Keynote Introduction

Photo of Edward Farmer, PhD, Strategic Communications Consultant, Genomics England , Strategic Communications Consultant , Genomics England
Edward Farmer, PhD, Strategic Communications Consultant, Genomics England , Strategic Communications Consultant , Genomics England

PLENARY KEYNOTE CO-PRESENTATION:
East London: A Global Hub for Digital Precision Medicine 

Photo of Professor Sir Mark Caulfield, MD, FRCP, FESC, FPharm, FBHS, FMedSci, Vice Principal for Health, Faculty of Medicine and Dentistry, Queen Mary University of London; Director, NIHR Barts Biomedical Research Centre , Professor Sir , Barts Life Sciences & William Harvey Research Institute , Barts Life Sciences & Queen Mary University of London
Professor Sir Mark Caulfield, MD, FRCP, FESC, FPharm, FBHS, FMedSci, Vice Principal for Health, Faculty of Medicine and Dentistry, Queen Mary University of London; Director, NIHR Barts Biomedical Research Centre , Professor Sir , Barts Life Sciences & William Harvey Research Institute , Barts Life Sciences & Queen Mary University of London
Photo of Tom Chittenden, PhD, DPhil, PStat, Honorary Professor, Digital Environment Research Institute, Queen Mary University of London; CSO, BullFrog AI , Chief Scientific Officer , BullFrog AI
Tom Chittenden, PhD, DPhil, PStat, Honorary Professor, Digital Environment Research Institute, Queen Mary University of London; CSO, BullFrog AI , Chief Scientific Officer , BullFrog AI

Barts Health NHS Trust and Queen Mary University of London (QMUL) are embarking on one of the world's most ambitious digital medicine initiatives. Director of the NIHR Barts Biomedical Research Centre, Prof Mark Caulfield, and newly appointed QMUL Honorary Professor Tom Chittenden will lay out this vision and its impact on patients and science. In one of the largest and most diverse NHS trusts, in the heart of the East London AI and medical research community, Barts and QMUL are investing £600m pounds to create new digital healthcare infrastructure and develop a world-leading open-access exascale causal AI computing platform. This will enable a newly detailed understanding of the biology of cancer, cardiovascular, and other diseases, driving cutting-edge drug and digital health development relevant to people of every continental ancestry. These assets will deliver the most advanced digital precision medicine to millions of people in local communities, and, through research and industry partnerships, to people and patients worldwide.   

Coffee Break in the Exhibit Hall with Poster Viewing

FAIR DATA PRINCIPLES: PRACTICAL USE-CASES AND LEARNINGS

Organizer's Remarks

Eileen Murphy, Conference Producer, Cambridge Healthtech Institute , Conference Producer , Cambridge Healthtech Institute

Chairperson's Remarks

Despoina Sousoni, PhD, Industry and Innovation Officer, ELIXIR-Hub , ELIXIR Industry and Innovation Officer , ELIXIR-Hub

Panel Moderator:

PANEL DISCUSSION:
Collaborative Efforts to Make Life Sciences Data More FAIR: Tools, Protocols, and Best Practices

Photo of Despoina Sousoni, PhD, Industry and Innovation Officer, ELIXIR-Hub , ELIXIR Industry and Innovation Officer , ELIXIR-Hub
Despoina Sousoni, PhD, Industry and Innovation Officer, ELIXIR-Hub , ELIXIR Industry and Innovation Officer , ELIXIR-Hub

Panelists:

Photo of Giovanni Nisato, PhD, Consultant, Project Manager FAIR implementation, Pistoia Alliance , Consultant - Project Manager FAIR implementation , Pistoia Alliance
Giovanni Nisato, PhD, Consultant, Project Manager FAIR implementation, Pistoia Alliance , Consultant - Project Manager FAIR implementation , Pistoia Alliance
Photo of Philippe Rocca-Serra, PhD, Senior Director FAIR Collaborations R&D, AstraZeneca, Cambridge UK; Associate Member of Faculty, Oxford e-Research Centre, University of Oxford , Senior Director, FAIR Collaboration AZ / Senior Research at Oxford e-Research Centre, UOXF , R&D Data Office / O , AstraZeneca / University of Oxford
Philippe Rocca-Serra, PhD, Senior Director FAIR Collaborations R&D, AstraZeneca, Cambridge UK; Associate Member of Faculty, Oxford e-Research Centre, University of Oxford , Senior Director, FAIR Collaboration AZ / Senior Research at Oxford e-Research Centre, UOXF , R&D Data Office / O , AstraZeneca / University of Oxford
Photo of Susanna-Assunta Sansone, PhD, Professor of Data Readiness, Department of Engineering Science; Academic Lead for Research Practice, University of Oxford , Professor of Data Readiness , University of Oxford
Susanna-Assunta Sansone, PhD, Professor of Data Readiness, Department of Engineering Science; Academic Lead for Research Practice, University of Oxford , Professor of Data Readiness , University of Oxford
Photo of Danielle Welter, PhD, Principal Data Analyst, Luxembourg National Data Service (LNDS) , Principal Data Analyst , Luxembourg National Data Service (LNDS)
Danielle Welter, PhD, Principal Data Analyst, Luxembourg National Data Service (LNDS) , Principal Data Analyst , Luxembourg National Data Service (LNDS)

Networking Lunch in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)

FAIR PRACTICES IN RESEARCH DATA MANAGEMENT TO ACCELERATE BIOMEDICAL DISCOVERY

Chairperson's Remarks

Ishwar Chandramouliswaran, Program Director, Office of Data Science Strategy, NIH , Program Director , Office of Data Science Strategy , NIH

Panel Moderator:

PANEL DISCUSSION:
FAIR Practices in Research Data Management to Accelerate Biomedical Discovery

Photo of Carole Goble, CBE FREng FBCS CITP, Professor, Computer Science, The University of Manchester; Joint Head, Node ELIXIR-UK , Professor , Computer Science , The University of Manchester
Carole Goble, CBE FREng FBCS CITP, Professor, Computer Science, The University of Manchester; Joint Head, Node ELIXIR-UK , Professor , Computer Science , The University of Manchester

Panelists:

Photo of Carole Goble, CBE FREng FBCS CITP, Professor, Computer Science, The University of Manchester; Joint Head, Node ELIXIR-UK , Professor , Computer Science , The University of Manchester
Carole Goble, CBE FREng FBCS CITP, Professor, Computer Science, The University of Manchester; Joint Head, Node ELIXIR-UK , Professor , Computer Science , The University of Manchester
Photo of Tomasz Miksa, PhD, Senior Researcher, SBA Research , Senior Researcher , SBA Research
Tomasz Miksa, PhD, Senior Researcher, SBA Research , Senior Researcher , SBA Research
Photo of Shivendra Naidoo, Senior Engagement Lead (Vendor Development), ORCID , Senior Engagement Lead - Vendor Development , ORCID
Shivendra Naidoo, Senior Engagement Lead (Vendor Development), ORCID , Senior Engagement Lead - Vendor Development , ORCID
Photo of Fotis Psomopoulos, PhD, Senior Researcher, INAB|CERTH , Senior Researcher , Institute of Applied Biosciences (INAB) , Centre for Research & Technology Hellas (CERTH)
Fotis Psomopoulos, PhD, Senior Researcher, INAB|CERTH , Senior Researcher , Institute of Applied Biosciences (INAB) , Centre for Research & Technology Hellas (CERTH)
Photo of Erik Schultes, FAIR Implementation Lead, GO FAIR Foundation; Senior Researcher, Leiden Academic Center for Drug Research , FAIR Implementation Lead , GO FAIR Foundation
Erik Schultes, FAIR Implementation Lead, GO FAIR Foundation; Senior Researcher, Leiden Academic Center for Drug Research , FAIR Implementation Lead , GO FAIR Foundation
Photo of Shelley Stall, Vice President, Open Science Leadership, American Geophysical Union (AGU) , Vice President, Open Science Leadership , American Geophysical Union (AGU)
Shelley Stall, Vice President, Open Science Leadership, American Geophysical Union (AGU) , Vice President, Open Science Leadership , American Geophysical Union (AGU)

Bio researchers require awareness of the effect that the environment has on research design and protocols. Collaboration between geoscientists, either directly or indirectly, provides the detailed information necessary to ensure successful research. At the AGU, the critical elements of FAIR data include 1) earth and environmental observational data, 2) the preservation repository selected for the data, and 3) the persistent identifier that is the beacon to the data and information about it. We will share the AGU’s work connecting researchers to these three critical elements, ensuring that research publications and data are linked to heighten reproducibility and transparency in science.

Close of Conference


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